Endocrine Abstracts

Introduction: Primary empty sella (PES) is often found incidentally during neuroradiological studies. Although pituitary function is usually normal in patients with PES, it could be associated with serious clinical conditions including different degrees of hypopituitarism. Post-operative empty sella (POES), the most common group, results from pituitary adenoma and their treatments. Our aim is to compare anterior pituitary functions and quality of life (QoL) with Short Form-36 ...

Introduction: Pituitary apoplexy results from haemorrhagic infarction of a pre-existing pituitary adenoma or within physiologically enlarged gland. Pituitary apoplexy during pregnancy is rare but serious event with significant morbidity and mortality if not recognised in time. Pituitary apoplexy is characterised by sudden onset of headache, nausea, vomiting, visual disturbances, eye movements restricted and varying degrees of pituitary insufficiency and accompanied by change o...

Introduction: Insulin resistance is the decrease sensitivity of tissues in the body to insulin effect. Obesity, advanced age, sedentary life and smoking are the factors leading to an increase in insulin resistance. In our study, we aimed to evaluate the relationship between the insulin resistance and smoking in individuals without advanced age, obesity, high blood glucose levels and hypertension.Materials and methods: We included in this study 100 patien...

Objective: Patients with hyperprolactinemia who require medical therapy are typically treated with dopamine agonists (DA). In most cases, medical therapy with DA normalizes the level of prolactin (PRL), restores gonadal function and fertility, and substantially reduces the size of the tumor. Here, we aimed to compare the efficacy of cabergoline (CAB) and bromocriptine (BRC) in hyperprolactinemic patients retrospectively.Methods: Retrospective analysis of...

Introduction: Different nutritional and environmental factors are responsible for pathogenesis of goiter but iodine deficiency is the most important factor. However, little is known about the natural course of benign thyroid nodules in euthyroid patients over time. Few studies have used ultrasonographic evaluation to address this issue, especially in iodine-deficient areas. In this study, we present the long-term follow-up of benign thyroid nodules in a moderately iodine-defic...

Introduction: Recent conducted studies show that clinical hypothyroidism (CH) has similar cardiovascular risk with subclinical hypothyroidism (SCH). Carotid intima media thickness (CIMT) that is an important marker of early atherosclerotic changes is an indicator of cardiovascular events. In our study, we evaluated CIMT in female patients, who have both CH and SCH, with similar age and demographic features.Materials and methods: We recruited 38 healthy f...

Objective: Most of the papillary thyroid microcarcinomas (PTMC) are incidentally discovered in pathological examination after the surgery of benign thyroid disorders. The purpose of the present study was to evaluate clinicopathologic features of incidental and nonincidental PTMC.Material and methods: We evaluated 56 patients with PTMC between 2003 and 2008 at the Division of Endocrinology of the Numune Training and Research Hospital. We analyzed the tumo...

Objective: Thyroid malignancy detected incidentally in patients who underwent surgery for thyrotoxicosis has been reported at different rates. The aim of this study was to investigate the rate of incidental thyroid carcinoma (ITC) in thyrotoxic patients underwent surgery in our institution.Methods: The prevalence of ITC was investigated in patients who underwent surgery for Graves’ disease (GD), toxic adenoma (TA) or toxic multinodular goiter (TMNG)...

Objective: We designed this study to evaluate whether visceral fat area (VFA), and subcutaneous fat area (SFA) are associated with atherosclerotic parameters in obese and non-obese subjects.Material and methods: Of 104 healthy volunteers were recruited for the study. Participitants were divided into two groups according to their body mass index (BMI). Group 1 has a BMI of <25 kg/m2 (n=31) and the BMI of the group 2 was ≥25 kg/...

Objective: Acromegaly is associated with an increased prevalence of colonic polyps. The aim of this study was to evaluate the prevalence of colonic polyps in acromegalic subjects, and also whether there is a relationship between insulin-like growth factor 1 (IGF-1), growth hormon (GH), fasting insulin plasma levels and the presence of polyps.Material and methods: Fifty-four consecutive acromegalic patients and 45 IBS patients were enrolled to study betwe...